>NC_002645_HCoV-229E_inf-1_nsp1_293..625_333bp_111aa
-------------------------MACNRVTLAVASDSEISANGCSTIAQAVRRYSEAA
SNGFRACR-----------------FVSLDLQDC--------------------------
--IVGIADDTYVMGL-------------------------------HG-NQTLFCNIMKF
-SDRPFMLHGWLVF------------------------------------------SNSN
YLLE---------EFDVVFGKRGGG
>NC_005831_HCoV-NL63_AmsterdamI_nsp1_287..616_330bp_110aa
-------------------------MFYNQVTLAVASDSEISGFGFAIPSVAVRTYSEAA
AQGFQACR-----------------FVAFGLQDC--------------------------
--VTGINDDDYVIAL-------------------------------TG-TNQLCAKILPF
-SDRPLNLRGWLIF------------------------------------------SNSN
YVLQ---------DFDVVFGHGAG-
>NC_002306_TGEV_PUR46-MAD_nsp1_315..638_324bp_108aa
-------------------------MSSKQFKILVNEDYQVNVPSLP-IRDVLQEIKYCY
RNGFEGYV-----------------FVPEYCRDL--------------------------
--VDCDRKDHYVIGV-------------------------------LG-NGVSDLKPVLL
-TEPSVMLQGFIVR------------------------------------------ANCN
GVLE---------DFDLKIARTG--
>NC_003436_PEDV_CV777_nsp1_297..626_330bp_110aa
-------------------------MASNHVTLAFANDAEISAFGFCTASEAVSYYSEAA
ASGFMQCR-----------------FVSLDLADT--------------------------
--VEGLLPEDYVMVV-------------------------------IG-TTKLSAYVDTF
-GSRPRNICGWLLF------------------------------------------SNCN
YFLE---------ELELTFGRRGG-
>DQ811787_PRCV_ISU-1_nsp1_304..627_324bp_108aa
-------------------------MSSKQFKILVNEDYQVNVPSLP-IRDVLQEIKYCY
RNGFEGYV-----------------FVPEYCRDL--------------------------
--VDCDRKDHYVIGV-------------------------------LG-NGVSNLKPVLL
-TEPSVMLQGFIVR------------------------------------------SNCN
GVLE---------DFDFKIARTG--
>AY994055_FIPV_79-1146_nsp1_311..640_330bp_110aa
-------------------------MSSKQFKILVNEDYQVNVPSLP-FRDALQEIKYCY
RNGFDGYV-----------------FVPEYRRDL--------------------------
--VDCNRKDHYVIGV-------------------------------LG-NGISDLKPVLL
-TEPSVMLQGFIVR------------------------------------------ANCN
GVLE---------DFDLKFARTGNG
>NC_009657_BtCoV-G1_BtCoV/512/2005_nsp1_294..623_330bp_110aa
-------------------------MASNHISLAFANDEEISAIGFGSVEEAVSYYSDAA
VNGFDQCR-----------------FVSLGLQDA--------------------------
--VVGVEDDDVVMLI-------------------------------TG-VTQLRAYLGTF
-GDRPLNLRGWLLF------------------------------------------SNCN
YFLE---------ELDLVFGRCGG-
>EF203064_Bat-CoV-HKU2_HKU2/GD/430/2006_nsp1_297..626_330bp_110aa
-------------------------MSINQLTLAVASDQEISAHGYPTMSDAVEHFSSSA
SHGFKDCR-----------------FVASGLQDI--------------------------
--VIGVEPSDFVVAL-------------------------------EG-DEILTAYIATF
-GARPRCLRGWLIP------------------------------------------SNSN
YVLE---------EFHVIFGKRGG-
>NC_005147_HCoV-OC43_OC43_nsp1_211..948_738bp_246aa
---MSKINKYGLELHWAPEFPWMFEDAEEKLDNPSSSEVDMICSTTA--QKLETDGICPE
NHVMVDCRRLLKQECCVQSSLIREIVMNASPYDLEVLLQDALQSREAVLVTTPLGMSLEA
CYVRGCNPKGWTMGLFRRRSVCNTGRCTVNKHVAYQLYMIDPAGVCLG-AGQFVGWVIPL
-AFMPVQSRKFIVPWVMYLRKRGEKG-AYNKDHGRGGFGHVYDFKVEDAYDQVHDEPKGK
FSKK---------AYALIRGYRG--
>NC_006577_CoV-HKU1A_N1_nsp1_206..871_666bp_222aa
---MIKTSKYGLGFKWAPEFRWLLPDAAEELASPMKSDEGGLCPSTG--QAMESVGFVYD
NHVKIDCRCILGQEWHVQSNLIRDIFVHEDLHVVEVLTKTAVKSGTAILIKSPLH-----
--SLGGFPKGYVMGL---------FRSYKTKRYVVHHLSMTTSTTNFG--EDFLGWIVPF
-GFMPSYVHKWFQFCRLY--------IEESDLIISNFKFDDYDFSVEDAYAEVHAEPKGK
YSQK---------AYALLRQYRG--
>AY884001_CoV-HKU1B_N2_nsp1_200..865_666bp_222aa
---MIKTSKYGLGFKWAPEFRWLLPDAAEELASPMKSDEGGLCPSTG--QAMESVGFVYD
NHVKIDCRCILGQEWHVQSNLIRDIFVHEDLHVVEVLTKTAVKSGTAILIKSPLH-----
--SLGGFPKGYVMGL---------FRSYKTKRYVVHHLSMTTSTTNFG--EDFLGWIVPF
-GFMPSYVHKWFQFCRLY--------IEESDLIISNFKFDDYDFSVEDAYAEVHAEPKGK
YSQK---------AYALLRQYRG--
>DQ339101_CoV-HKU1C_N5_nsp1_200..865_666bp_222aa
---MIKTSKYGLGFKWAPEFRWLLPDAAEELASPMKSDEGGLCPSTG--QAMESVGFVYD
NHVKIDCRCILGQEWHVQSNLIRDIFVHEDLHVVEVLTKTAVKSGTAILIKSPLH-----
--SLGGFPKGYVMGL---------FRSYKTKRYVVHHLSMTTSTTNFG--EDFFGWIVPF
-GFMPSYVHKWFQFCRLY--------IEESDLIISNFKFDDYDFSVEAAYAEVHAEPKGK
YSQK---------AYALLRQYRG--
>NC_003045_BCoV_BCoV-ENT_nsp1_211..948_738bp_246aa
---MSKINKYGLELHWAPEFPWMFEDAEEKLDNPSSSEVDIVCSTTA--QKLETGGICPE
NHVMVDCRRLLKQECCVQSSLIREIVMNTRPYDLEVLLQDALQSREAVLVTPPLGMSLEA
CYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIPL
-AFMPVQSRKFIVPWVMYLRKCGEKG-AYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGK
FSKK---------AYALIRGYRG--
>NC_001846_MHV_MHV-A59_nsp1_210..950_741bp_247aa
---MAKMGKYGLGFKWAPEFPWMLPNASEKLGNPERSEEDGFCPSAA--QEPKVKGKTLV
NHVRVNCSRLPALECCVQSAIIRDIFVDEDPQKVEASTMMALQFGSAVLVKPSKRLSIQA
WTNLGVLPKTAAMGLFKRVCLCNTRECSCDAHVAFHLFTVQPDGVCLG-NGRFIGWFVPV
-TAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYDFNVEDACEEVHLNPKGK
YSCK---------AYALLKGYRG--
>NC_007732_PHEV_VW572_nsp1_211..948_738bp_246aa
---MSKINKYGLELYWAPEFPWMFEDAEEKLDNPSSSEVDIVCSTTA--QKLETGGICPE
NHVMVDCRRLLKQECCVQSSLIREIVMNTRPYDLEVLLQDALQSREAVLVTPPLGMSLEA
CYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIPL
-AFMPAQSRKFIVPWVMYLRKCGDKG-AYNKDHKRGGFEHVYNFKVEDAYDQVHDEPKGK
FSRK---------AYALLRGYRG--
>EF424621_AntelopeCoV_US/OH1/2003WD1418_nsp1_196..933_738bp_246aa
---MSKINKYGLELHWAPEFPWMFEDAEEKLDNPSSSEVDIVCSTTA--QKLETGGICPE
NHVMVDCRRLLKQECCVQSSLIREIVMNTRPYDLEVLLQDALQSREAVLVTPPLGMSLEA
CYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIPL
-AFMPVQSRKFIVPWVMYLRKCGEKG-AYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGK
FSKK---------AYALIRGYRG--
>EF424622_GiCoV_US/OH3-TC/2006_nsp1_195..932_738bp_246aa
---MSKINKYGLELHWAPEFPWMFEDAEEKLDNPSSSEVDIVCSTTA--QKLETGGICPE
NHVMVDCRRLLKQECCVQSSLIREIVMNTRPYDLEVLLQDALQSREAVLVTPPLGMSLEA
CYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFG-AGQFVGWVIPL
-AFMPVQSRKFIVPWVMYLRKCGEKG-AYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGK
FSKK---------AYALIRGYRG--
>NC_004718_SARS-human_Tor2_nsp1_265..804_540bp_180aa
----MESLVLGVNE-----------KTHVQLSLPVLQVRDVLVRGFG--DSVEEALSEAR
EHLKNGTCGLVELEKGVLPQLEQP-YVFIKRSDA--------------------------
---LSTNHGHKVVEL-----------------------VAEMDGIQYGRSGITLGVLVPH
VGETPIAYRNVLLR--------------KNGNKGAGGHSYGIDLKSYDLGDELGTDPIED
YEQNWNTKHGSGALRELTRELNGG-
>AY304488_SARS-civet_SZ16_nsp1_250..789_540bp_180aa
----MESLVLGVNE-----------KTHVQLSLPVLQVRDVLVRGFG--DSVEEALSEAR
EHLKNGTCGLVELEKGVLPQLEQP-YVFIKRSDA--------------------------
---LSTNHGHKVVEL-----------------------VAEMDGIQYGRSGITLGVLVPH
VGETPIAYRNVLLR--------------KNGNKGAGGHSYGTDLKSYDLGDELGTDPIED
YEQNWNTKHGSGALRELTRELNGG-
>NC_009694_SARS-bat_HKU3-1_nsp1_262..801_540bp_180aa
----MESLVLGVNE-----------KTHVQLSLPVLQVRDVLVRGFG--DSVEEALSEAR
EHLKNGTCGLVELEKGVLPQLEQP-YVFIKRSDA--------------------------
---LSTNHGHKVVEL-----------------------VAELDGIQFGRSGITLGVLVPH
VGETPIAYRNVLLR--------------KNGNKGAGGHSFGIDLKSYDLGDELGTDPIED
YEQNWNTKHGSGALRELTRELNGG-
>AY545919_SARS-badger_CFB/SZ/94/03_nsp1_244..783_540bp_180aa
----MESLVLGVNE-----------KTHVQLSLPVLQVRDVLVRGFG--DSVEEALSEAR
EHLKNGTCGLVELEKGVLPQLEQP-YVFIKRSDA--------------------------
---LSTNHGHKVVEL-----------------------VAEMDGIQYGRSGITLGVLVPH
VGETPIAYRNVLLR--------------KNGNKGAGGHSYGIDLKSYDLGDELGTDPIED
YEQNWNTKHGSGALRELTRELNGG-
>NC_009019_Bat-CoV-HKU4_B04f HKU41_nsp1_267..851_585bp_195aa
MLSKASVTTQGARGKYRAELYNEKRSDHVACTVPLCDTDDMACKLTPWFEDGETAFNQVS
SILKEKGKIL---------------FVPMHMQRA-------------MKFLPGPRVYLVE
RLTGGMLSKHFLVNQ------------------LAYKDQVGAAMMRTTLNAKPLGMFFPY
DSSLETGEYTFLLR-----------KNGLGGQLFRERPWDRKETPYVEILDDLEADPTGK
YSQ------------NLLKKLIGG-
>NC_009020_Bat-CoV-HKU5_LMH3f HKU51_nsp1_261..845_585bp_195aa
MSFVAGVAPQGARGKYRAELNTEKRTDHVSLKASLCDAGDLVLKISPWFMDGESAYKHVS
EQLSKGSKLL---------------FVPQTLKGF-------------IRHLPGPRVYLVE
RLTGGTYSDPFMVNQ------------------LAYQNAAGEGVIGTTLQGKRVGMFFPF
DADLVTGEFQFLLR-----------KKGFGGNRFRDAPWDYNWTPYSDLMDALEADPCGK
YSQ------------SLLKKLVGG-
>NC_009021_Bat-CoV-HKU9_BF_005I HKU91_nsp1_229..753_525bp_175aa
MEGVPDPPKL---------------KSMVVTTLKWCDPF-ANPNVTGWDIPIEEALEYAK
QQLRTPEPQLV--------------FVPYYLSHA--------------------------
---PGISGDRVVITD-------SIWYATNFGWQPIRELAMDKDGVRYG-RGGTHGVLLPM
-QDPSFIMGDIDIQIRKY-------GIGANSPPDVLPLWDGFSDPGPDVGPYLDFPDNCC
PTKP--------------KAKRGG-